Lab test
Methylmalonic Acid Blood Test
Methylmalonic Acid Blood Test is a laboratory test you can request directly. A methylmalonic acid blood test measures a substance that can build up when vitamin B12 is low. It helps clinicians evaluate certain types of anemia and nerve symptoms.
Lab requirements in Methylmalonic Acid Blood Test
Here is what you need before ordering and completing the Methylmalonic Acid Blood Test. Review each item and confirm the details with the collection lab.
- Physician's order
- Included. A physician's order is required for lab testing and is provided for you by our partner's physicians — no referral from your own doctor is needed.
- Fasting
- Fasting is required for this test — follow the collection lab's instructions.
- Preparation
- Preparation instructions can vary, so follow the specific directions provided by the collection lab. This may include fasting or avoiding certain supplements before the test.
- Sample & visit
- A blood and/or urine sample is collected; the visit usually takes about 10 minutes.
- Identification
- Bring the lab requisition form from your account. The collection lab may also ask for a government-issued photo ID.
- Turnaround
- 1-3 business days
- Availability
- Our partner lab does not serve ND, RI, NY, NJ, MD or HI. Confirm availability for your location with the collection lab.
Before you go
- Order your test before visiting a lab, then use the requisition form in your account.
- Print the requisition form, or fax it to the lab directly from your account.
- No scheduling is needed — visit the collection lab during its normal business hours.
- A blood and/or urine sample is collected; the visit usually takes about 10 minutes.
- Bring a government-issued photo ID in case the lab requests it.
- Results are posted to your secure account within 1–3 business days.
Requirements are summarized from our partner lab's published policies. Preparation and availability can change — confirm current instructions with the collection lab before your visit.
What this test is
This test measures the amount of methylmalonic acid in the blood. Methylmalonic acid is a byproduct of certain metabolic processes that require vitamin B12. When vitamin B12 is insufficient, methylmalonic acid levels can rise.
What it measures
- Methylmalonic acid — reflects vitamin B12 activity in the body
What the test involves
The test requires a standard blood draw from a vein in your arm, usually at a laboratory or clinic. The sample is then sent to a lab for analysis.
Why it is often ordered
A clinician may order this test to help assess vitamin B12 status, especially when symptoms such as fatigue, tingling, or balance problems are present. It can also be used to monitor certain conditions or treatments that affect B12 levels.
Preparation
Preparation instructions can vary, so follow the specific directions provided by the collection lab. This may include fasting or avoiding certain supplements before the test.
How results are reported
Results are typically reported as a numeric value with a reference range. Reference ranges can differ between laboratories, so your results should be interpreted in the context of the lab that performed the test.
Before you go
- Whether fasting is required before the blood draw
- If any medications or supplements should be avoided
- When and how results will be provided
FAQ
Frequently asked questions
What does a high methylmalonic acid level mean?
A high level may suggest that vitamin B12 is low or not working properly in the body. However, other factors can affect the result, so a clinician will interpret it along with your symptoms and other tests.
Do I need to fast for this test?
Fasting requirements depend on the laboratory and the specific instructions you receive. Always follow the preparation directions given by the collection lab.
How long does it take to get results?
Results are usually available within a few business days, but timing can vary by laboratory. The lab or your clinician will inform you when results are ready.
Can I take vitamin supplements before this test?
Some supplements can affect methylmalonic acid levels, so it is important to tell the lab and your clinician about any supplements you take. They may advise you to stop certain supplements temporarily before testing.
Related
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Locations
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